Switch from Pulse? No reason not to. Use Wireplumber instead of pipewire-session-manager, and consider installing pipewire-pulse if any of your scripts rely on pactl (or rewrite them to use wpctl, which does much the same as pactl).

As for Easyeffects, use the flatpak package to avoid dependency issues.

I’m using pipewire with easyeffects and they both work great.

For pipewire I’ve installed all the available compatibility layers: pipewire-pulse, pipewire-alsa, pipewire-jack, as well as every lib32 variant. Without all of these some apps would not work via pipewire.

As for easyeffects, depending on your distro and how you install it, you might need to install the plugins separately. Otherwise the app will open but it won’t be able to actually apply any effects. First time I tried to use it I was confused about this.

Yea it just-works, I’ve had zero issues with it, easyeffects too

I love it. I can run my microphone through noise-canceling when using video call software that doesn’t have its own noise-canceling. I can run an audio compressor over mpv if the movie does that loud explosion/quiet talking thing. You can assign each application a different effect stack.

Tried it on bazzite, seemed to work without issues.